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A B2-AR agonist selectively induces cAMP accumulation in CHO cells expressing the B2-AR over the B1- and B3-ARs (EC50s 0.4 398 and 794 nM for the human receptors respectively) inhibits contractions induced by electrical stimulation in isolated superfused guinea pig trachea strips inhibits histamine-induced bronchospasms in guinea pigs when administered via nebulization (EC50 30 UM)
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An antiparasitic agent reduces the proliferation of T. brucei (IC50 63.1 nM) but not T. cruzi L. infantum P. falciparum or human MRC-5 fibroblasts (IC50s >6000 nM for all) reduces peripheral blood parasite levels below detection limits and increases survival in a mouse model of T. brucei infection at 50 mg/kg twice per day
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Chemglass deep-well 24-well microplate with 16 mL V-bottom wells, provided sterile and nest-packed for laboratory sample processing and storage. Includes a 24-well plastic comb and is suitable for automated workflows.
24 wells
16 mL nominal volume per well
V-bottom well geometry
Square well top for secure sealing
Manufactured from USP Class VI polypropylene
Sterile, nest-packed format
Includes a 24-well plastic comb
Suitable for storage, extraction, and automated processing
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A multi-kinase inhibitor selectively inhibits MET VEGFR2 Axl and Mer (IC50s 3 15 5.8 and 0.6 nM respectively) over serine/threonine kinases for which it has no activity but does inhibit 28 additional RTKs (IC50s 3-54 nM) and additional kinases by greater than 70 at 1 UM inhibits the proliferation of SNU-5 cells (IC50 98.9 nM) and HUVECs (IC50 10.4 nM) reduces tumor volume and intratumoral MET phosphorylation in NCI H441 and SNU-5 mouse xenograft models at 3 and 10 mg/kg increases the number of peripheral B cells and CD4 T cells and decreases the number of peripheral myeloid cells in an MC-38 syngeneic mouse model of colon carcinoma at 30 mg/kg
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Bilirubin Standard has been tested and formulated to work exclusively with Cayman’s Total and Direct Bilirubin Colorimetric Assay Kit (Item No. 701720).
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An analytical reference standard categorized as a triazolobenzodiazepine an active metabolite of rilmazafone intended for research and forensic applications
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A cationic lipid has been used for transfection of DNA RNA and other negatively charged molecules into eukaryotic cells has been used in the composition of small unilamellar liposomes formulated as gene delivery vectors for gene therapy
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