Microplate Lids
Cayman Chemical Stndard DIluent asy Reagen 4mL
A multi-kinase inhibitor inhibits FLT3 CSF1R c-Kit FGFR1 FGFR3 VEGFR1 -2 and -3 PDFGRa and PDGFRB (IC50s 1 36 2 8 9 10 13 8 27 and 210 nM respectively) inhibits the proliferation of human multiple myeloma cell lines expressing mutant but not wild-type FGFR3 (IC50s 90-550 and >2500 nM respectively) decreases FGF-induced ERK1/2 phosphorylation and induces apoptosis in patient-derived multiple myeloma cells at 500 nM inhibits bFGF-induced angiogenesis in a Matrigel™ plUG assay in mice at 3-300 mg/kg for 8 days reduces tumor growth in KM12L4A DU145 and MV4-11 mouse xenograft models (ED50s 17 23 and 3 mg/kg per day respectively)
Glass Expansion PuraFlex Transfer Tube GAZ08-FB13-105
PuraFlex Transfer Tube GAZ08-FB13-105 Sourced from Glass Expansion
Electron Microscopy Sciences MicroWell Lid for 96-Well Plate
Vented lids for MicroWell plates allow for gas exchange and have condensation rings to control evaporation and retain condensate.
Cayman Chemical ThIol CysteIn Stndard 1ea
An internal standard for the quantification of acetyl-coenzyme A by GC- or LC-MS
Sigma Aldrich Fine Chemicals Biosciences CRNG 384WE LO VOL MICROPL 10PK
NC3354943 CRNG 384WE LO VOL MICROPL 10PK
Cayman Chemical pNA Stndard 50uL
A riboside form of nicotinamide a precursor of NAD and a source of vitamin B3 increases intracellular and mitochondrial NAD content in C2C12 Hepa1.6 and HEK293 cells in a concentration-dependent manner at concentrations ranging from 1-1000 M decreases acetylation of FOXO1 and SOD2 but not tubulin increases NAD levels in liver and skeletal muscle and prevents body weight gain in mice fed a high-fat diet when used at a dose of 400 mg/kg per day increases NAD in the cerebral cortex and reduces cognitive deterioration in a transgenic mouse model of Alzheimers disease